ewaybill for non registered states

Under gst we can easily send the stocks to all over India.
but with eway bill can we do same or we need to register gstin in different states. e.g. A delhi trader not registered in Karnataka.. Need to send Goods on sale basis to Karnataka customer. can he do that it or gstin in Karnataka is must? and in this case can supplier issue eway bill from delhi? if not what options he has for eway bill?
Pls advise