Applicability of E-way Bill & Invoicing Method

XYZ Co. Ltd. has appointed ABC Private Limited company to procure / Manufacture promotional activities goods like T-shirts & Caps and send directly to its distributors & Retailers pan India.

Once ABC has completed all the deliveries then after confirmation they will issue a single invoice to XYZ Co. Limited

Now how does ABC company send the material if the individual consignment value is more than 50,000 and how E-way bills will be issued. Is it ok to issue one consolidated invoice after all Invoices or what will be case? 

Please Guide..